Sodium ion → 5-Bromo-2-chloro-1-(5-(2-pyridyl)-2-thienylmethyl)benzene

HRID 696901Notes

Reaction equation

[BH4-:22].[Br:1][c:2]1[cH:3][cH:4][c:5]([Cl:21])[c:6]([CH:8]([OH:9])[c:10]2[s:11][c:12](-[c:15]3[n:16][cH:17][cH:18][cH:19][cH:20]3)[cH:13][cH:14]2)[cH:7]1.[Na+:23].[OH:24][C:25]([C:26]([F:27])([F:28])[F:29])=[O:30]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([Cl:21])[c:6]([CH2:8][c:10]2[s:11][c:12](-[c:15]3[n:16][cH:17][cH:18][cH:19][cH:20]3)[cH:13][cH:14]2)[cH:7]1

Participants

Reactant 4

HCID 923Sodium ion

HCID 6422Trifluoroacetic acid

HCID 28123Borohydride

HCID 666073255-Bromo-2-chlorophenyl-5-(2-pyridyl)-2-thienylmethanol

Product 1

HCID 666072295-Bromo-2-chloro-1-(5-(2-pyridyl)-2-thienylmethyl)benzene

Sources & evidence

ORD record: ord-f0f642b63bd54105a14f4775a6da6b03
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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