Hydrochloric Acid → tert-Butyl [(4-{2-[2-(azetidin-1-ylmethyl)pyridin-4-yl]-4-chlorophenoxy}-2,5-difluorophenyl)sulfonyl]1,3-thiazol-4-ylcarbamate
Reaction equation
[C:46]([O:47][BH-:48]([O:49][C:50](=[O:51])[CH3:52])[O:53][C:54](=[O:55])[CH3:56])(=[O:57])[CH3:58].[C:60](=[O:61])([OH:62])[O-:63].[Cl:1][c:2]1[cH:3][c:4](-[c:33]2[cH:34][c:35]([CH:39]=[O:40])[n:36][cH:37][cH:38]2)[c:5]([O:6][c:7]2[cH:8][c:9]([F:30])[c:10]([S:14](=[O:15])(=[O:16])[N:17]([C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[c:25]3[n:26][cH:27][s:28][cH:29]3)[cH:11][c:12]2[F:13])[cH:31][cH:32]1.[Cl:65][CH2:66][Cl:67].[ClH:41].[NH:42]1[CH2:43][CH2:44][CH2:45]1.[Na+:59].[Na+:64]>>[Cl:1][c:2]1[cH:3][c:4](-[c:33]2[cH:34][c:35]([CH2:39][N:42]3[CH2:43][CH2:44][CH2:45]3)[n:36][cH:37][cH:38]2)[c:5]([O:6][c:7]2[cH:8][c:9]([F:30])[c:10]([S:14](=[O:15])(=[O:16])[N:17]([C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[c:25]3[n:26][cH:27][s:28][cH:29]3)[cH:11][c:12]2[F:13])[cH:31][cH:32]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-8f2c9e170c674d60bbd0504616f77152
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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