1,2-Dichloroethane → 3-Benzyl-1-(4-fluoro-phenyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione

HRID 696960Notes

Reaction equation

HRID 696960 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[C:9](=[O:33])[N:10]([c:26]2[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]2)[C:11]2([C:12]1=[O:13])[CH2:14][CH2:15][N:16]([CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[CH2:17][CH2:18]2.[CH3:45][OH:46].[Cl:34][CH2:35][CH2:36][Cl:37].[Cl:38][C:39]([O:40][CH:41]([Cl:42])[CH3:43])=[O:44]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[C:9](=[O:33])[N:10]([c:26]2[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]2)[C:11]2([C:12]1=[O:13])[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]2

Participants

5

Reactant 4

HCID 111,2-DichloroethaneHCID 887MethanolHCID 5213051-Chloroethyl chloroformateHCID 54268940HCID 54268940, compound

Product 1

HCID 536628233-Benzyl-1-(4-fluoro-phenyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione

Sources & evidence

ORD record
ord-1a72f662bde04b15a57eb8a252fac0ff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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