Imidazole → 4-[4-(1H-imidazol-1-ylmethyl)benzenesulfonyl]-1-[1-(tert-butoxycarbonyl)piperidin-4-ylmethyl]-2-piperazinone
Reaction equation
[Br:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([S:9](=[O:10])(=[O:11])[N:12]2[CH2:13][C:14](=[O:32])[N:15]([CH2:18][CH:19]3[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:23][CH2:24]3)[CH2:16][CH2:17]2)[cH:7][cH:8]1.[C:33](=[O:34])([O-:35])[O-:36].[K+:37].[K+:38].[O:44]=[CH:45][N:46]([CH3:47])[CH3:48].[nH:39]1[cH:40][n:41][cH:42][cH:43]1>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]([S:9](=[O:10])(=[O:11])[N:12]2[CH2:13][C:14](=[O:32])[N:15]([CH2:18][CH:19]3[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:23][CH2:24]3)[CH2:16][CH2:17]2)[cH:7][cH:8]1)[n:39]1[cH:40][n:41][cH:42][cH:43]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f5eaf86f7b5f495986da3384d9e078fc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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