Bicarbonate Ion → 3-[(4-Chlorophenyl)-[3-[1-(3,5-difluorophenyl)-2-fluoro-2-methylpropyl]azetidin-1-yl]methyl]benzonitrile
Reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([c:9]2[cH:10][c:11]([C:12]#[N:13])[cH:14][cH:15][cH:16]2)[N:17]2[CH2:18][CH:19]([CH:21]([C:22]([CH3:23])([CH3:24])[OH:25])[c:26]3[cH:27][c:28]([F:33])[cH:29][c:30]([F:32])[cH:31]3)[CH2:20]2)[cH:6][cH:7]1.[Cl:48][CH2:49][Cl:50].[FH:40].[Na+:42].[Na+:47].[O-:43][C:44]([OH:45])=[O:46].[OH-:41].[n:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([c:9]2[cH:10][c:11]([C:12]#[N:13])[cH:14][cH:15][cH:16]2)[N:17]2[CH2:18][CH:19]([CH:21]([C:22]([CH3:23])([CH3:24])[F:40])[c:26]3[cH:27][c:28]([F:33])[cH:29][c:30]([F:32])[cH:31]3)[CH2:20]2)[cH:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-b3ae554455154b19a40b30506e38e27a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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