Dimethylformamide → (RS)-4-(5-bromo-2-fluoro-phenyl)-4-methyl-oxazolidin-2-one

HRID 697397Notes

Reaction equation

HRID 697397 reaction equation
[Ag+:31].[B-:26]([F:27])([F:28])([F:29])[F:30].[Br:1][c:2]1[cH:3][c:4]([C:9]([CH2:10][I:11])([CH3:12])[N:13]=[C:14]=[O:15])[c:5]([F:8])[cH:6][cH:7]1.[CH3:16][C:17]([CH3:18])([CH3:19])[OH:20].[CH3:21][N:22]([CH3:23])[CH:24]=[O:25]>>[Br:1][c:2]1[cH:3][c:4]([C:9]2([CH3:12])[CH2:10][O:20][C:14](=[O:15])[NH:13]2)[c:5]([F:8])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 6386tert-ButanolHCID 26255TetrafluoroborateHCID 104755Silver cationHCID 58563022(RS)-4-bromo-1-fluoro-2-(2-iodo-1-isocyanato-1-methyl-ethyl)-benzene

Product 1

HCID 58563120(RS)-4-(5-bromo-2-fluoro-phenyl)-4-methyl-oxazolidin-2-one

Sources & evidence

ORD record
ord-af562e4d5f1c4fcbb761dd0c950a18c7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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