Borohydride → 1-Boc-2-hydroxymethyl-4-methylpyrrolidine

HRID 697417Notes

Reaction equation

[BH4-:18].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[O:16][CH3:17])[CH2:10][CH:11]([CH3:13])[CH2:12]1.[Li+:19]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:14][OH:15])[CH2:10][CH:11]([CH3:13])[CH2:12]1

Participants

Reactant 3

HCID 28123Borohydride

HCID 28486Lithium ion

HCID 138227471-tert-Butyl 2-methyl (2S,4R)-4-methylpyrrolidine-1,2-dicarboxylate

Product 1

HCID 211005041-Boc-2-hydroxymethyl-4-methylpyrrolidine

Sources & evidence

ORD record: ord-6c024a2f18c94c75bd6c4e4307d1afa8
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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