Methanol → 5-Chloro-2-methylamino-4-(3-(trifluoromethyl)piperidin-1-yl)aniline
Reaction equation
[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[CH3:28][OH:29].[Cl:1][c:2]1[cH:3][c:4]([N+:20]([O-:21])=[O:22])[c:5]([NH:6][CH3:7])[cH:8][c:9]1[N:10]1[CH2:11][CH:12]([C:16]([F:17])([F:18])[F:19])[CH2:13][CH2:14][CH2:15]1>>[Cl:1][c:2]1[cH:3][c:4]([NH2:20])[c:5]([NH:6][CH3:7])[cH:8][c:9]1[N:10]1[CH2:11][CH:12]([C:16]([F:17])([F:18])[F:19])[CH2:13][CH2:14][CH2:15]1Participants
4
Sources & evidence
- ORD record
- ord-d1b60293c638434ea21c8a150890540a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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