Tetrahydrofuran → 5-Bromo-4-fluoro-1-[tris(1-methylethyl)silyl]-1H-pyrrolo[2,3-b]pyridine
Reaction equation
[Br:26][C:27]([Br:28])([Br:29])[Br:30].[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH:21]([Li:22])([CH2:23][CH3:24])[CH3:25].[F:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[cH:9][cH:10]2>>[F:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[Br:26])[n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[cH:9][cH:10]2Participants
5
Sources & evidence
- ORD record
- ord-4666492b9c3d440796c0220eefbf8e6e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…