Diisopropylamine → Diethyl 2,6-bis(trifluoromethyl)-4-chloro-3,5-pyridinedicarboxylate
Reaction equation
[CH3:2][CH:3]([N-:4][CH:5]([CH3:6])[CH3:7])[CH3:8].[CH3:47][O:48][CH2:49][CH2:50][O:51][CH3:52].[CH3:9][CH2:10][CH2:11][CH2:12][Li:13].[CH:14]([NH:15][CH:16]([CH3:17])[CH3:18])([CH3:19])[CH3:20].[Cl:41][C:42](=[O:43])[O:44][CH2:45][CH3:46].[F:21][C:22]([c:23]1[n:24][c:25]([C:35]([F:36])([F:37])[F:38])[cH:26][c:27]([Cl:34])[c:28]1[C:29](=[O:30])[O:31][CH2:32][CH3:33])([F:39])[F:40].[Li+:1]>>[F:21][C:22]([c:23]1[n:24][c:25]([C:35]([F:36])([F:37])[F:38])[c:26]([C:42](=[O:43])[O:44][CH2:45][CH3:46])[c:27]([Cl:34])[c:28]1[C:29](=[O:30])[O:31][CH2:32][CH3:33])([F:39])[F:40]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-8ffda2366acc4d69824c5da38995afcb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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