Tetrahydrofuran → tert-Butyl 2-(prop-2-yn-1-yl)pyrrolidine-1-carboxylate

HRID 698059Notes

Reaction equation

HRID 698059 reaction equation
[Br:1][C:2](=[CH:3][CH2:4][CH:5]1[N:6]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:7][CH2:8][CH2:9]1)[Br:17].[CH2:18]([Li:19])[CH2:20][CH2:21][CH3:22].[O:23]1[CH2:24][CH2:25][CH2:26][CH2:27]1>>[CH:2]#[C:3][CH2:4][CH:5]1[N:6]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:7][CH2:8][CH2:9]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 86657052HCID 86657052, compoundHCID 178418339Butyllithium

Product 1

HCID 21964030tert-Butyl 2-(prop-2-yn-1-yl)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-566067a200944bc3a7bfda5afd4f0f79
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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