Tetrahydrofuran → (4-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-iodo-phenyl)-methanone
Reaction equation
[Br:6][c:7]1[cH:8][n:9]([CH:17]2[CH2:18][CH2:19][CH2:20][CH2:21]2)[c:10]2[n:11][cH:12][n:13][c:14]([Cl:16])[c:15]12.[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[I:22][c:23]1[cH:24][c:25]([C:26](=[O:27])[N:28]([O:29][CH3:30])[CH3:31])[cH:32][cH:33][cH:34]1>>[c:7]1([C:26]([c:25]2[cH:24][c:23]([I:22])[cH:34][cH:33][cH:32]2)=[O:27])[cH:8][n:9]([CH:17]2[CH2:18][CH2:19][CH2:20][CH2:21]2)[c:10]2[n:11][cH:12][n:13][c:14]([Cl:16])[c:15]12Participants
5
Sources & evidence
- ORD record
- ord-ee9e6d40c5084988bd92273e0c0fd274
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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