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HRID69849

反应详情

EQUATION

反应方程式

HRID 69849 的结构方程式

REACTANTS

反应物

2
结构：O=[N+]([O-])c1cc(Cl)ccc1F
HCID67660

4-Chloro-1-fluoro-2-nitrobenzene

C6H3ClFNO2

结构：CC(C)(C)OC(=O)NC1CCNCC1
HCID723833

4-(N-Boc-amino)piperidine

C10H20N2O2

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)NC1CCN(c2ccc(Cl)cc2[N+](=O)[O-])CC1
HCID60507369

未命名化合物

收率 95%

PROCEDURE

实验过程

Method 1 was followed using 1 eq each of 4-chloro-1-fluoro-2-nitrobenzene, 4-N-Boc-aminopiperidine, and TEA yielding tert-butyl 1-(4-chloro-2-nitrophenyl)piperidin-4-ylcarbamate (95%). LCMS (m/z): 356.1 (MH+); LC Rt=3.43 min.