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HRID69866

反应详情

EQUATION

反应方程式

HRID 69866 的结构方程式

REACTANTS

反应物

1
结构：CC(C)(C)OC(=O)NC1CCN(c2ccc(C(F)(F)F)cc2[N+](=O)[O-])CC1
HCID60507337

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)NC1CCN(c2ccc(C(F)(F)F)cc2N)CC1
HCID69043886

未命名化合物

收率 97%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Following the method of Example 49 (Method 2), tert-butyl 1-(2-nitro-4-(trifluoromethyl)phenyl)piperidin-4-yl-carbamate in MeOH was reduced yielding tert-butyl 1-(2-amino-4-(trifluoromethyl)phenyl)piperidin-4-ylcarbamate (97%). LCMS (m/z): 360.1 (MH+); LC Rt=3.20 min.