HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 69046899, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 3-Bromo-4-nitropyridine N-oxide | HCID 548521 | — |
| Reactant | 3-(Boc-amino)piperidine | HCID 4233041 | — |
| Product | HCID 69046899 | HCID 69046899 | 65% |
Reaction Steps
The method of Example 88 (Method 4) was followed using 1 eq each of 3-bromo-4-nitropyridine-N-oxide, 3-N-Boc-amino piperidine and diisopropylethylamine yielding tert-butyl 1-(4-nitropyridin-3-yl)piperidin-3-ylcarbamate (65%). LCMS (m/z): 339.1 (MH+); LC Rt=2.88 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822497B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-6d9044794987445aa0eb865443368ee6 |
| Source note | uspto-grants-2014_09 |