HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69046899, compound → Tert-butyl 1-(4-aminopyridin-3-yl)piperidin-3-ylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69046899 | HCID 69046899 | — |
| Solvent | Ethanol ethylacetate | HCID 21584252 | — |
| Product | Tert-butyl 1-(4-aminopyridin-3-yl)piperidin-3-ylcarbamate | HCID 69095089 | 79% |
Reaction Steps
The method of Example 90 (Method 5) was followed using 1 eq of tert-butyl 1-(4-nitropyridin-3-yl)piperidin-3-ylcarbamate in 1:1 ethanol/ethyl acetate at 30 psi for 72 hours, yielding tert-butyl 1-(4-aminopyridin-3-yl)piperidin-3-ylcarbamate (79%). LCMS (m/z): 293.1 (MH+); LC Rt=2.14 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822497B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-05f5aac40ac24acda8ecad55c1e45bf8 |
| Source note | uspto-grants-2014_09 |