Isopropanol → tert-Butyl 4-(4-(6-Bromo-4-methyl-3-oxo-3,4-dihydropyrazin-2-ylamino)phenyl)piperidine-1-carboxylate

HRID 698859Notes

Reaction equation

HRID 698859 reaction equation
[Br:21][c:22]1[c:23](=[O:30])[n:24]([CH3:29])[cH:25][c:26]([Br:28])[n:27]1.[CH:31]([OH:32])([CH3:33])[CH3:34].[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([CH:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[cH:6][cH:7]1)[c:22]1[c:23](=[O:30])[n:24]([CH3:29])[cH:25][c:26]([Br:28])[n:27]1

Participants

4

Reactant 3

HCID 3776IsopropanolHCID 130629693,5-Dibromo-1-methyl-1H-pyrazin-2-oneHCID 21940085tert-Butyl 4-(4-aminophenyl)piperidine-1-carboxylate

Product 1

HCID 58043998tert-Butyl 4-(4-(6-Bromo-4-methyl-3-oxo-3,4-dihydropyrazin-2-ylamino)phenyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-9e00d86af5c24784b10cb30df9a1f65e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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