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HRID69900

反应详情

EQUATION

反应方程式

HRID 69900 的结构方程式

REACTANTS

反应物

1
结构：CC(C)(C)OC(=O)NC1CCN(c2ccncc2[N+](=O)[O-])CC1O[Si](C)(C)C(C)(C)C
HCID77419822

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)NC1CCN(c2ccncc2N)CC1O[Si](C)(C)C(C)(C)C
HCID77419825

未命名化合物

收率 99%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CCO
溶剂HCID702

Ethanol

C2H6O

结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

Following Method 2 of Example 49, (+/−)-tert-butyl 3-(tert-butyldimethylsilyloxy)-1-(3-nitropyridin-4-yl)piperidin-4-ylcarbamate in ethanol and ethyl acetate (1:1, 0.1 M solution) was reduced yielding (+/−)-tert-butyl 1-(3-aminopyridin-4-yl)-3-(tert-butyldimethylsilyloxy)piperidin-4-ylcarbamate, (>99%). LCMS (m/z): 423.3 (MH+); LC Rt=3.62 min.