huagongshe.com
HRID69917

反应详情

EQUATION

反应方程式

HRID 69917 的结构方程式

REACTANTS

反应物

1
结构：CC(C)(C)[Si](C)(C)O[C@H]1CCCN(c2ccncc2[N+](=O)[O-])C1
HCID69095957

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)c1nccc(N2CCC[C@H](O[Si](C)(C)C(C)(C)C)C2)c1N
HCID86669191

未命名化合物

收率 67%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Following Method 2 of Example 49, (S)-4-(3-(tert-butyl dimethylsilyloxy)piperidin-1-yl)-3-nitropyridine in ethanol was reduced yielding tert-butyl (S)-4-(3-(tert-butyldimethylsilyloxy)piperidin-1-yl)pyridin-3-amine (67% yield 3 steps). LCMS (m/z): 308.2 (MH+); LC Rt=3.47 min.