Sodium ion → 3-tert-butoxycarbonyl-7-chloro-6-(1-cyano-cyclopropylthio)-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Reaction equation
[Br:34][CH2:35][CH2:36][Br:37].[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[CH2:19][CH2:20][c:21]2[c:22]([c:25]([S:30][CH2:31][C:32]#[N:33])[c:26]([Cl:29])[cH:27][cH:28]2)[CH2:23][CH2:24]1.[CH3:1][Si:2]([N-:3][Si:4]([CH3:5])([CH3:6])[CH3:7])([CH3:8])[CH3:9].[CH3:43][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1.[Na+:10].[O:38]=[CH:39][N:40]([CH3:41])[CH3:42]>>[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[CH2:19][CH2:20][c:21]2[c:22]([c:25]([S:30][C:31]3([C:32]#[N:33])[CH2:35][CH2:36]3)[c:26]([Cl:29])[cH:27][cH:28]2)[CH2:23][CH2:24]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-20e29e972eee48b1aaa7e191e316de93
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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