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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 699231Generated: October 29, 2026

Ethyl bromoacetate → (RS)-(4-cyano-phenylamino)-[5-ethoxy-3-(1-ethoxycarbonylmethyl-piperidin-4-yloxy)-2-fluoro-phenyl]-acetic acid ethyl ester

https://huagongshe.com/reaction/699231

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl bromoacetateHCID 7748—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
Reactant(RS)-(4-cyano-phenylamino)-[5-ethoxy-2-fluoro-3-(piperidin-4-yloxy)-phenyl]-acetic acid ethyl esterHCID 69923727—
Product(RS)-(4-cyano-phenylamino)-[5-ethoxy-3-(1-ethoxycarbonylmethyl-piperidin-4-yloxy)-2-fluoro-phenyl]-acetic acid ethyl esterHCID 69923157—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-36a8cd7ecb9e4e01b5a8dc1df4e3e65a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)