Ethyl bromoacetate → (RS)-(4-cyano-phenylamino)-[5-ethoxy-3-(1-ethoxycarbonylmethyl-piperidin-4-yloxy)-2-fluoro-phenyl]-acetic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH:5]([c:6]1[c:7]([F:22])[c:8]([O:15][CH:16]2[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]2)[cH:9][c:10]([O:12][CH2:13][CH3:14])[cH:11]1)[NH:23][c:24]1[cH:25][cH:26][c:27]([C:30]#[N:31])[cH:28][cH:29]1)=[O:32].[CH2:40]([CH3:41])[O:42][C:43]([CH2:44][Br:45])=[O:46].[CH2:47]1[O:48][CH2:49][CH2:50][CH2:51]1.[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39]>>[CH2:1]([CH3:2])[O:3][C:4]([CH:5]([c:6]1[c:7]([F:22])[c:8]([O:15][CH:16]2[CH2:17][CH2:18][N:19]([CH2:44][C:43]([O:42][CH2:40][CH3:41])=[O:46])[CH2:20][CH2:21]2)[cH:9][c:10]([O:12][CH2:13][CH3:14])[cH:11]1)[NH:23][c:24]1[cH:25][cH:26][c:27]([C:30]#[N:31])[cH:28][cH:29]1)=[O:32]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-36a8cd7ecb9e4e01b5a8dc1df4e3e65a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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