Hydrochloric Acid → 1-(1-(4-(N-tert-butyloxycarbonyl-4-piperidinyloxy)-5-fluoro-2-methoxy-benzoyl) piperidin-4-yl)-4H-3,1-benzoxazin-2(1H)-one

HRID 699342Notes

Reaction equation

HRID 699342 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][c:17]([O:25][CH3:26])[c:18]([C:19](=[O:20])[OH:21])[cH:22][c:23]2[F:24])[CH2:12][CH2:13]1.[ClH:27].[NH:28]1[CH2:29][CH2:30][CH:31]([N:34]2[C:35](=[O:44])[O:36][CH2:37][c:38]3[c:39]2[cH:40][cH:41][cH:42][cH:43]3)[CH2:32][CH2:33]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][c:17]([O:25][CH3:26])[c:18]([C:19](=[O:21])[N:28]3[CH2:29][CH2:30][CH:31]([N:34]4[C:35](=[O:44])[O:36][CH2:37][c:38]5[c:39]4[cH:40][cH:41][cH:42][cH:43]5)[CH2:32][CH2:33]3)[cH:22][c:23]2[F:24])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 98641174-(N-t-butyloxycarbonyl-4-piperidinyloxy)-5-fluoro-2-methoxybenzoic acidHCID 107047401-(Piperidin-4-yl)-1h-benzo[d][1,3]oxazin-2(4h)-one

Product 1

HCID 190735311-(1-(4-(N-tert-butyloxycarbonyl-4-piperidinyloxy)-5-fluoro-2-methoxy-benzoyl) piperidin-4-yl)-4H-3,1-benzoxazin-2(1H)-one

Sources & evidence

ORD record
ord-9637a02495ea4790af789e2d4986775a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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