HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69044134, compound → HCID 69047258, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69044134 | HCID 69044134 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 69047258 | HCID 69047258 | 90% |
Reaction Steps
Method 26 was followed using benzyl 4-(2-(di-BOC-amino)-6-methylpyrimidin-4-yl)pyridin-3-ylcarbamate (1.0 equiv.), Pd/C (20% by weight) in EtOAc yielding 4-(3-aminopyridin-4-yl)-N,N-di-BOC-6-methylpyrimidin-2-amine in 90% yield. LCMS (m/z): 402.3 (MH+); LC Rt=3.0 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822497B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-3eb9c96f8f5640388b6c4b91399fdc86 |
| Source note | uspto-grants-2014_09 |