HRID69951

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cc1cc(-c2ccncc2NC(=O)OCc2ccccc2)nc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n1

HCID69044134

未命名化合物

PRODUCTS

生成物

结构：Cc1cc(-c2ccncc2N)nc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n1

HCID69047258

未命名化合物

收率 90%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

Method 26 was followed using benzyl 4-(2-(di-BOC-amino)-6-methylpyrimidin-4-yl)pyridin-3-ylcarbamate (1.0 equiv.), Pd/C (20% by weight) in EtOAc yielding 4-(3-aminopyridin-4-yl)-N,N-di-BOC-6-methylpyrimidin-2-amine in 90% yield. LCMS (m/z): 402.3 (MH+); LC Rt=3.0 min.