2-hydroxy-3-(1H-imidazol-5-yl)propanoic acid → 2-hydroxy-1-[4-[2-(2-hydroxyphenyl)-7-methylquinazolin-4-yl]piperazin-1-yl]-3-(1H-imidazol-5-yl)propan-1-one
Reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([N:19]3[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]3)[n:7][c:8](-[c:12]3[c:13]([OH:18])[cH:14][cH:15][cH:16][cH:17]3)[n:9][c:10]2[cH:11]1.[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[Cl:43][CH2:44][Cl:45].[OH2:46].[OH:25][CH:26]([C:27](=[O:28])[OH:29])[CH2:30][c:31]1[cH:32][n:33][cH:34][nH:35]1>>[CH3:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([N:19]3[CH2:20][CH2:21][N:22]([C:27]([CH:26]([OH:25])[CH2:30][c:31]4[cH:32][n:33][cH:34][nH:35]4)=[O:28])[CH2:23][CH2:24]3)[n:7][c:8](-[c:12]3[c:13]([OH:18])[cH:14][cH:15][cH:16][cH:17]3)[n:9][c:10]2[cH:11]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-3acce1ab3fe6444ab857f1116da890e7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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