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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 700137Generated: October 25, 2026

Tetrahydrofuran → 5-(Trifluoromethyl)-3-((trimethylsilyl)ethynyl)-pyridin-2-amine

https://huagongshe.com/reaction/700137

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethylsilylacetyleneHCID 66111—
Reactant3-Iodo-5-(trifluoromethyl)pyridin-2-amineHCID 15350914—
ReactantHCID 178479804HCID 178479804—
Product5-(Trifluoromethyl)-3-((trimethylsilyl)ethynyl)-pyridin-2-amineHCID 46736871—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-76530b718f3d4c2ea3a1305407955738
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)