HRID700137

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID8471

Triethylamine

C6H15N

HCID24350

Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

CuI

HCID66111

Trimethylsilylacetylene

C5H10Si

HCID15350914

3-Iodo-5-(trifluoromethyl)pyridin-2-amine

C6H4F3IN2

结构：Cl[Pd-]([PH](c1ccccc1)(c1ccccc1)c1ccccc1)[PH](c1ccccc1)(c1ccccc1)c1ccccc1

HCID178479804

未命名化合物

PRODUCTS

生成物

HCID46736871

5-(Trifluoromethyl)-3-[(trimethylsilyl)ethynyl]pyridin-2-amine

C11H13F3N2Si

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-76530b718f3d4c2ea3a1305407955738
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (3/10)

反应 SMILES

[CH3:13][Si:14]([CH3:15])([CH3:16])[C:17]#[CH:18].[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[Cu:31][I:32].[I:1][c:2]1[c:3]([NH2:12])[n:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1.[c:33]1([PH:34]([Pd-:35]([Cl:36])[PH:37]([c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)([c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)[c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)([c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[cH:68][cH:69][cH:70][cH:71][cH:72]1>>[c:2]1([C:18]#[C:17][Si:14]([CH3:13])([CH3:15])[CH3:16])[c:3]([NH2:12])[n:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1