Diisopropylamine → 1-(5-Bromo-2-fluoro-3-pyridinyl)-2-[4-(dimethylamino)phenyl]ethanone
Reaction equation
[Br:13][c:14]1[cH:15][cH:16][c:17]([F:20])[n:18][cH:19]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:21][N:22]([c:23]1[cH:24][cH:25][c:26]([CH2:29][C:30](=[O:31])[N:32]([O:33][CH3:34])[CH3:35])[cH:27][cH:28]1)[CH3:36].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[Br:13][c:14]1[cH:15][c:16]([C:30]([CH2:29][c:26]2[cH:25][cH:24][c:23]([N:22]([CH3:21])[CH3:36])[cH:28][cH:27]2)=[O:31])[c:17]([F:20])[n:18][cH:19]1Participants
6
Sources & evidence
- ORD record
- ord-2202a3e4e178478a95eb4396a9dae074
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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