Methanol → [7-(4-t-Butoxycarbonylpiperazin-1-yl)-3,4-dihydro-1(1H)-isoquinolinone-2-yl]acetic acid

HRID 700243Notes

Reaction equation

HRID 700243 reaction equation
[CH2:1]([CH3:2])[CH:3]([C:4](=[O:5])[O-:6])[N:7]1[C:8](=[O:30])[c:9]2[cH:10][c:11]([N:17]3[CH2:18][CH2:19][N:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:21][CH2:22]3)[cH:12][cH:13][c:14]2[CH2:15][CH2:16]1.[CH3:33][OH:34].[Li+:32].[OH-:31]>>[CH2:3]([C:4](=[O:5])[OH:6])[N:7]1[C:8](=[O:30])[c:9]2[cH:10][c:11]([N:17]3[CH2:18][CH2:19][N:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:21][CH2:22]3)[cH:12][cH:13][c:14]2[CH2:15][CH2:16]1

Participants

5

Reactant 4

HCID 887MethanolHCID 961HydroxideHCID 28486Lithium ionHCID 178454760HCID 178454760, compound

Product 1

HCID 11794693[7-(4-t-Butoxycarbonylpiperazin-1-yl)-3,4-dihydro-1(1H)-isoquinolinone-2-yl]acetic acid

Sources & evidence

ORD record
ord-bee47274d04f401e84468bf55644de61
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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