Dimethyl Sulfoxide → 4-Cyanomethyl-1-diphenylmethylpiperidine

HRID 700290Notes

Reaction equation

HRID 700290 reaction equation
[C-:1]#[N:2].[CH3:30][S:31](=[O:32])[CH3:33].[Na+:29].[Na+:3].[O-:25][C:26]([OH:27])=[O:28].[c:4]1([CH:10]([N:11]2[CH2:12][CH2:13][CH:14]([CH2:17][Cl:18])[CH2:15][CH2:16]2)[c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:5][cH:6][cH:7][cH:8][cH:9]1>>[C:1](#[N:2])[CH2:17][CH:14]1[CH2:13][CH2:12][N:11]([CH:10]([c:4]2[cH:5][cH:6][cH:7][cH:8][cH:9]2)[c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[CH2:16][CH2:15]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 5975CyanideHCID 538573511-Diphenylmethyl-4-chloromethylpiperidine

Product 1

HCID 184257274-Cyanomethyl-1-diphenylmethylpiperidine

Sources & evidence

ORD record
ord-69cfe93cf67343cf846436626d85ae87
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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