Bromide ion → 2-(5-(6-Amino-2-methylpyrimidin-4-yl)-6-(5-fluoro-6-methoxypyridin-3-ylamino)pyridin-3-yl)propan-2-ol
Reaction equation
[Br-:28].[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:29][Mg+:30].[NH2:1][c:2]1[cH:3][c:4](-[c:9]2[cH:10][c:11]([C:25]([CH3:26])=[O:27])[cH:12][n:13][c:14]2[NH:15][c:16]2[cH:17][n:18][c:19]([O:23][CH3:24])[c:20]([F:22])[cH:21]2)[n:5][c:6]([CH3:8])[n:7]1>>[NH2:1][c:2]1[cH:3][c:4](-[c:9]2[cH:10][c:11]([C:25]([CH3:26])([OH:27])[CH3:29])[cH:12][n:13][c:14]2[NH:15][c:16]2[cH:17][n:18][c:19]([O:23][CH3:24])[c:20]([F:22])[cH:21]2)[n:5][c:6]([CH3:8])[n:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-d68a0af1e5064483aaf6158723776d51
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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