HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-5-dibenzylamino-1-methylpiperidin-2-one → HCID 28064098, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-5-dibenzylamino-1-methylpiperidin-2-one | HCID 59708472 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 28064098 | HCID 28064098 | 101.6% |
Reaction Steps
450 mg (S)-5-dibenzylamino-1-methyl-piperidin-2-one are suspended in 25 ml of methanol and hydrogenated with 150 mg Pd/C 10% under a pressure of 3 bar and at a temperature of 60° C. After 16 hours the catalyst is removed by suction filtering and the filtrate is evaporated to dryness. 190 mg of the product are obtained as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822474B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-361341bef66e4e7bbc5870aec89c9a28 |
| Source note | uspto-grants-2014_09 |