Hydrochloric Acid → [6-(2-Hydroxy-ethylamino)-3-methyl-5-(3-trifluoromethyl-phenyl)-pyridin-2-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone

HRID 701009Notes

Reaction equation

HRID 701009 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][CH2:10][NH:11][c:12]1[c:13](-[c:32]2[cH:33][c:34]([C:38]([F:39])([F:40])[F:41])[cH:35][cH:36][cH:37]2)[cH:14][c:15]([CH3:31])[c:16]([C:18](=[O:19])[N:20]2[CH2:21][CH2:22][CH:23]([N:26]3[CH2:27][CH2:28][CH2:29][CH2:30]3)[CH2:24][CH2:25]2)[n:17]1.[CH3:45][OH:46].[ClH:42].[H:43][H:44]>>[OH:8][CH2:9][CH2:10][NH:11][c:12]1[c:13](-[c:32]2[cH:33][c:34]([C:38]([F:39])([F:40])[F:41])[cH:35][cH:36][cH:37]2)[cH:14][c:15]([CH3:31])[c:16]([C:18](=[O:19])[N:20]2[CH2:21][CH2:22][CH:23]([N:26]3[CH2:27][CH2:28][CH2:29][CH2:30]3)[CH2:24][CH2:25]2)[n:17]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 67025369[6-(2-Benzyloxy-ethylamino)-3-methyl-5-(3-trifluoromethyl-phenyl)-pyridin-2-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanoneHCID 178418361HCID 178418361, compound

Product 1

HCID 44547500[6-(2-Hydroxy-ethylamino)-3-methyl-5-(3-trifluoromethyl-phenyl)-pyridin-2-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone

Sources & evidence

ORD record
ord-d209bc1d277e4b708eeb89f4a9a50f28
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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