Dichloromethane → Methyl 2-[1-[2-[tert-butyl(diphenyl)silyl]oxy-1-cyclopropylethyl]-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]-3-methylsulfonyloxypropanoate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][CH:8]([CH:9]1[CH2:10][CH2:11]1)[N:12]1[C:13](=[O:40])[C:14]([CH3:32])([CH:33]([C:34](=[O:35])[O:36][CH3:37])[CH2:38][OH:39])[CH2:15][CH:16]([c:25]2[cH:26][c:27]([Cl:31])[cH:28][cH:29][cH:30]2)[CH:17]1[c:18]1[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]1)([c:41]1[cH:42][cH:43][cH:44][cH:45][cH:46]1)[c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[CH3:53][CH2:54][N:55]([CH2:56][CH3:57])[CH2:58][CH3:59].[CH3:60][S:61]([Cl:62])(=[O:63])=[O:64].[Cl:65][CH2:66][Cl:67]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][CH:8]([CH:9]1[CH2:10][CH2:11]1)[N:12]1[C:13](=[O:40])[C:14]([CH3:32])([CH:33]([C:34](=[O:35])[O:36][CH3:37])[CH2:38][O:39][S:61]([CH3:60])(=[O:63])=[O:64])[CH2:15][CH:16]([c:25]2[cH:26][c:27]([Cl:31])[cH:28][cH:29][cH:30]2)[CH:17]1[c:18]1[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]1)([c:41]1[cH:42][cH:43][cH:44][cH:45][cH:46]1)[c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-0adc1a84355e4f55b967c972747d07a3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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