Chlorotrimethylsilane → 2-Methoxy-5-trifluoromethyl-3-trimethylsilanyl-pyridine
Reaction equation
[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:13][O:14][c:15]1[n:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]1.[CH3:25][Si:26]([CH3:27])([CH3:28])[Cl:29].[CH:6]([NH:7][CH:8]([CH3:9])[CH3:10])([CH3:11])[CH3:12].[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1>>[CH3:13][O:14][c:15]1[n:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][c:20]1[Si:26]([CH3:25])([CH3:27])[CH3:28]Participants
6
Sources & evidence
- ORD record
- ord-1eb5a1b8daf347e1a16a96da33074c1a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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