Acetonitrile → 3-(2,2-Difluoro-propionylamino)-5-(5-methyl-pyridin-2-yl)-benzoic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([c:4]1[cH:5][c:6]([NH2:17])[cH:7][c:8](-[c:10]2[n:11][cH:12][c:13]([CH3:16])[cH:14][cH:15]2)[cH:9]1)=[O:18].[CH3:26][CH2:27][N:28]=[C:29]=[N:30][CH2:31][CH2:32][CH2:33][N:34]([CH3:35])[CH3:36].[CH3:47][C:48]#[N:49].[F:19][C:20]([C:21](=[O:22])[OH:23])([CH3:24])[F:25].[OH:37][n:38]1[c:39]2[c:40]([cH:41][cH:42][cH:43][cH:44]2)[n:45][n:46]1>>[CH3:1][O:2][C:3]([c:4]1[cH:5][c:6]([NH:17][C:21]([C:20]([F:19])([CH3:24])[F:25])=[O:22])[cH:7][c:8](-[c:10]2[n:11][cH:12][c:13]([CH3:16])[cH:14][cH:15]2)[cH:9]1)=[O:18]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6969ebef30e34ce4b8cd84b54b9ad40b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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