Trifluoroacetic acid → 4-(5-(((4-Phenylpiperidin-4-yl)methoxy)methyl)pyridine-3yl)benzonitrile
Reaction equation
[BH:23]([OH:24])[OH:25].[Br:1][c:2]1[cH:3][n:4][cH:5][c:6]([CH2:8][O:9][CH2:10][C:11]2([c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[cH:7]1.[C:26](#[N:27])[c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1.[F:34][C:35]([F:36])([F:37])[C:38]([OH:39])=[O:40]>>[c:2]1(-[c:31]2[cH:30][cH:29][c:28]([C:26]#[N:27])[cH:33][cH:32]2)[cH:3][n:4][cH:5][c:6]([CH2:8][O:9][CH2:10][C:11]2([c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-01e8fad823f44385b6083e584dd17514
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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