Acetonitrile → 2-Amino-6-methyl-5-[(4-trifluoromethylphenyl)ethynyl]benzonitrile
Reaction equation
[CH3:24][CH2:25][N:26]([CH2:27][CH3:28])[CH2:29][CH3:30].[CH3:32][C:33]#[N:34].[Cu:35].[F:13][C:14]([c:15]1[cH:16][cH:17][c:18]([I:21])[cH:19][cH:20]1)([F:22])[F:23].[I-:31].[NH2:1][c:2]1[c:3]([C:4]#[N:5])[c:6]([CH3:12])[c:7]([C:10]#[CH:11])[cH:8][cH:9]1>>[NH2:1][c:2]1[c:3]([C:4]#[N:5])[c:6]([CH3:12])[c:7]([C:10]#[C:11][c:18]2[cH:17][cH:16][c:15]([C:14]([F:13])([F:22])[F:23])[cH:20][cH:19]2)[cH:8][cH:9]1Participants
7
Sources & evidence
- ORD record
- ord-92922bad30d147d389a547da9c0b5717
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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