HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 701784Generated: October 27, 2026
Hydrochloric Acid → Ethyl 4-[2-chloro-5-(2,3-difluoro-6-methoxybenzyloxy)-4-methoxyphenylamino]-2-methoxypyrimidine-5-carboxylate
https://huagongshe.com/reaction/701784
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Ethyl 4-chloro-2-methoxypyrimidine-5-carboxylate | HCID 22760998 | — |
| Reactant | 2-Chloro-5-(2,3-difluoro-6-methoxybenzyloxy)-4-methoxyaniline | HCID 59309639 | — |
| Product | Ethyl 4-[2-chloro-5-(2,3-difluoro-6-methoxybenzyloxy)-4-methoxyphenylamino]-2-methoxypyrimidine-5-carboxylate | HCID 68515564 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (3/10) |
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| ORD ID | ord-710005ddae19440d8a4542033c645108 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (3/10) |
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