Dichloromethane → 3,3-Difluoro-1,3′-biazetidine

HRID 701849Notes

Reaction equation

HRID 701849 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([N:12]2[CH2:13][C:14]([F:16])([F:17])[CH2:15]2)[CH2:11]1)([CH3:5])([CH3:6])[CH3:7].[Cl:18][CH2:19][Cl:20].[F:21][C:22]([F:23])([F:24])[C:25]([OH:26])=[O:27]>>[NH:8]1[CH2:9][CH:10]([N:12]2[CH2:13][C:14]([F:16])([F:17])[CH2:15]2)[CH2:11]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 59606024[1,3′-Biazetidine]-1′-carboxylic acid, 3,3-difluoro-, 1,1-dimethylethyl ester

Product 1

HCID 596054253,3-Difluoro-1,3′-biazetidine

Sources & evidence

ORD record
ord-290cc97174e4458aad72b1748e4c8f91
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…