Hydrochloric Acid → 5-amino-6-chloro-2-ethyl-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyridine-8-carboxamide

HRID 702893Notes

Reaction equation

HRID 702893 reaction equation
[CH3:32][CH2:33][OH:34].[CH3:35][OH:36].[ClH:31].[ClH:37].[NH2:1][c:2]1[c:3]([Cl:30])[cH:4][c:5]([C:13](=[O:14])[NH:15][CH2:16][CH:17]2[CH2:18][CH2:19][N:20]([C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[CH2:21][CH2:22]2)[c:6]2[n:7]1[cH:8][c:9]([CH2:11][CH3:12])[n:10]2>>[NH2:1][c:2]1[c:3]([Cl:30])[cH:4][c:5]([C:13](=[O:14])[NH:15][CH2:16][CH:17]2[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]2)[c:6]2[n:7]1[cH:8][c:9]([CH2:11][CH3:12])[n:10]2

Participants

5

Reactant 4

HCID 313Hydrochloric Acid2×HCID 702EthanolHCID 887MethanolHCID 22236502Tert-butyl 4-({[(5-amino-6-chloro-2-ethylimidazo[1,2-a]pyridin-8-yl)carbonyl]amino}methyl)piperidine-1-carboxylate

Product 1

HCID 99496125-amino-6-chloro-2-ethyl-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyridine-8-carboxamide

Sources & evidence

ORD record
ord-4dffde0beacb4cffa5beeb8c61146ada
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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