反应详情

Following the procedure of Example 4, 2,6-bis-(1,1-dimethylethyl)4-mercaptophenol (2.38 g, 0.01 mole) and (1-oxo-2-propenyl)morpholine(1.41 g, 0.01 mole) in methanol (75 ml) were combined with triethylamine (1.5 ml) and stirred for 12 hours at room temperature. The solvent was evaporated under a nitrogen stream leaving an orange oil which was chromatographed over silica. The product was recrystallized from a mixture of hexane, ethyl ether and methanol and the resu-ting white solid dried to yield the title compound, m.p. about 136.5°-137.5° C.

1. customThe solvent was evaporated under a nitrogen stream
2. customleaving an orange oil which
3. customwas chromatographed over silica
4. customThe product was recrystallized from a mixture of hexane, ethyl ether and methanol
5. customthe resu-ting white solid dried