反应详情

4-(2-Hydroxyethyl)-2(1H)-quinolinone is prepared from methyl 2-oxo-1,2-dihydro-4-quinolineacetate (prepared in 3.3.) according to the procedure described in 1.3. It is a solid, melting point 213°-5° C. A catalytic hydrogenation of this compound is performed with Adams+ platinum to obtain (±)-4-(2-hydroxyethyl)-3,4-dihydro-2(1H)-quinolinone.