反应详情

To 100 ml absolute ethanol, was added 5.0 g of 1H-indol-1-amine, 5.0 g of 4-chloro-5-cyanopyrimidine and 5 ml of triethylamine. After stirring at ambient temperature for 20 hours, the mixture was poured into 400 ml water, stirred for five minutes, then extracted with ethyl acetate. The organic layer was washed with water, then dried (saturated NaCl, anhydrous MgSO4).

1. stirringstirred for five minutes
2. extractionextracted with ethyl acetate
3. washThe organic layer was washed with water
4. dry with materialdried (saturated NaCl, anhydrous MgSO4)