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HRID703688

反应详情

EQUATION

反应方程式

HRID 703688 的结构方程式

REACTANTS

反应物

1
结构：CCCCCCCCCCC[C@H](C[C@H](O)[C@H](CCCCCC)C(=O)OCc1ccccc1)OC1CCCCO1
HCID67935914

未命名化合物

PRODUCTS

生成物

1
结构：CCCCCCCCCCC[C@H](C[C@H](O)[C@H](CCCCCC)C(=O)O)OC1CCCCO1
HCID57099235

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

(1.O.h) 430 mg of benzyl (2S 3S,5R)-2-hexyl-3-hydroxy-5-[(tetrahydro-2H-pyran-2-yl)oxy]hexadecanoate in 10 ml of THF are treated with Pd/C 10% and hydrogenated for 3 hours. The catalyst is filtered off and, after evaporation of the filtrate, the crude product is chromatographed on silica gel. There is obtained (2S,3S,5R)-2-hexyl-3-hydroxy-5-[(tetrahydro-2H -pyran-2-yl)oxy]hexadecanoic acid.

WORKUP

后处理

  1. filtrationThe catalyst is filtered off
  2. customafter evaporation of the filtrate
  3. customthe crude product is chromatographed on silica gel