HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroacetate → HCID 22669299, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroacetate | HCID 7295 | — |
| Reactant | 4-(Trifluoromethyl)aniline | HCID 9964 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Product | HCID 22669299 | HCID 22669299 | 59.2% |
Reaction Steps
4-Trifluoromethylaniline (5.84 g), methyl chloroacetate (13.1 g) and sodium bicarbonate (3 g) were treated according to the method of Intermediate 5. The product was purified by FCC eluting with System B (1:3) to give the title compound (5.00 g), t.l.c. (System B, 1:3) Rf 0.32.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04985427 |
| Source dataset | uspto-grants-1991_01 |
| ORD ID | ord-3f6bb2a4e37f4df091dc0aafc0ed1a21 |
| Source note | uspto-grants-1991_01 |