Methyl Isocyanate → HCID 54355381, compound

HRID 703806Notes

Reaction equation

HRID 703806 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:9]([CH2:11][C:12]([O:14][CH3:15])=[O:13])[NH2:10])[CH:6]=[CH:7][CH:8]=1.[CH3:16][N:17]=[C:18]=[O:19]>C(#N)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:9]([CH2:11][C:12]([O:14][CH3:15])=[O:13])[NH:10][C:18]([NH:17][CH3:16])=[O:19])[CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 12228Methyl IsocyanateHCID 53873990HCID 53873990, compound

Product 1

HCID 54355381HCID 54355381, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A solution of methyl [1-(3-methoxyphenyl)hydrazino]acetate (1.6 g) and methyl isocyanate (0.9 ml) in acetonitrile (20 ml) was heated under reflux for 1 h. The solvent was removed in vacuo and the residue was treated with ether to give the title compound (1.8 g) as a solid, m.p. 145°-146°.

Workup

  1. temperatureunder reflux for 1 h
  2. customThe solvent was removed in vacuo
  3. additionthe residue was treated with ether

Sources & evidence

ORD record
ord-ed98e318cb954589b186d1d1e54d3a87
Source dataset
uspto-grants-1991_01
Patent number
US04985427

Reaction notes

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