Methyl Isocyanate → HCID 20074946, compound

Participants

Reaction Steps

Methyl [1-(4-methoxyphenyl)hydrazino]acetate (1.50 g) was treated with methyl isocyanate (0.85 ml) and then with sodium methoxide (from sodium (0.33 g) in methanol (15 ml)) according to the method of Example 1. The product was purified by recrystallisation from ethyl acetate to give the title compound (703 mg), m.p. 179°-181°, t.l.c. (ether) Rf 0.5.

Provenance & Evidence