Hydrochloric Acid → HCID 20075032, compound

Participants

Reaction Steps

A solution of 2 g (5.3 mmol) of ethyl 2-[3-(1-methyl-1H-imidazol-2-yl)-2H-1-benzopyran-6-yl]oxy-2-methylpropanoate in 30 ml of absolute ethanol is treated with gaseous HCl for 15 min, with external cooling. The solution is treated, under vigorous stirring, with 100 ml of ether. The precipitate is filtered, washed with ether and dried under vacuum, giving 1.95 g of ethyl 2-[3-(1-methyl-1H-imidazol-2-yl)-2H-1-benzopyran-6-yl]oxy-2-methylpropanoate hydrochloride, m.p. 154°-156° C.

Provenance & Evidence